Molecular Biologist – Synthetic Biology

– Molecular Biologist – Synthetic Biologist
– Salary: Up to £48,000 D.o.E. plus excellent benefits including Share Options, 10% pension, and life assurance, medical cover plus others.
– Location: Central London
– Fantastic Opportunity to Join a Leading and Innovative Synthetic Biology Organisation
– PhD or Equivalent or Other Qualification Combined With Research Experience in Molecular Biology ESSENTIAL
– In Depth Knowledge of E.coli ESSENTIAL
– Experience of using E.coli with hard to express proteins (e.g. mammalian proteins) ESSENTIAL

Summary
This is an exciting opportunity for a creative scientist to join a growing company that is dedicated to the research of synthetic biology, who are at the cutting edge of a field that has great potential. The role has been created by the expansion of the company following the success of their research into the optimisation of Biological systems, producing high value products. This is a challenging yet exciting role to become a key member of this growing company, assisting with the research into the unique and exciting field of Synthetic Biology. 

The Company
The company was founded in 2011 by some of the leading minds in their field, with the aim to create a platform technology for the engineering of complex biological processes for use across multiple industrial sectors. They are at the cutting edge of research into Biological problems providing solutions to these by using their unique approach combining theory, computation, automation and experimentation. Over the last few years they have developed as a company to generate multiple revenue streams and grow not only in terms of employee numbers but also their presence in the industry. They synthetically engineer microbes to produce high value biological products such as proteins (e.g. enzymes), biopharmaceuticals, and biologically based chemicals for example fine and specialty chemicals. The company prides themselves on their innovative approach using the knowledge of their
employees to create new and innovative methods driving forward their research. They believe the field of Synthetic Biology offers massive potential with the potential to benefit the world improving human health delivering cleaner sources of chemicals and fuels. 

The Role
The successful candidate will join a world-class team of laboratory and computational scientists, building their platform for the rational engineering of biological systems to make high value products such as Biopharmaceuticals. This entails generating complex genetic constructs then testing them in microbial hosts using multifactorial experimental designs and sophisticated analytical methods. They currently use E.coli as their main host thus the need to have experience of working with this to express mammalian proteins. This laboratory-based scientist will be expected to work closely with their lab colleagues, in particular bioprocess / fermentation scientists, with our computational scientists and external partners and collaborators.

You will be required to work autonomously, so it is important for you to be able to use your own initiative. While there are other scientists in the department who can provide analytical input, it would be helpful if you have a knowledge of biochemical assays (e.g. ELISAs) and / or analytical techniques such as HPLC, GC and GC-MS.

Experience
The successful applicant must have a PhD or equivalent experience in a relevant subject, such as Molecular Biology / Biochemistry / Biotechnology, if you do have some post doc or industrial experience this is advantageous but not essential to your application. You will need to have the ability to generate complex gene constructs and test them in microbial hosts using multifactorial experimental designs and sophisticated analytical methods. 

You must have experience with biological / biochemical assays and analytical methods, together with expertise in the use of Escherichia coli. You will need to be conversant in scaled microbial processes and must be able to collaborate with your lab colleagues, in-house computational scientists and external partners and collaborators. If you have experience of programming during your education or other experience or worked in an automated environment then this is advantageous to your application.

We are looking for an innovative, creative scientist who enjoys problem-solving and is keen to be part of major new scientific research. If you feel you meet this description,

Keywords
Biochemical, Microbial, Yeast, E.coli, ELISA, HPLC, GC, GC-MS, Gene, Gene Construct, Gene Knockout, Assay, Assay Development, Biotech, Biotechnology, Industrial biotechnology, Biology, Biochemistry, Molecular Biology, Molecular Biochemist, Synthetic, Synthetic Biology, Enzyme, Protein, Prokaryote, PhD, Research.

This is a Permanent Position